Bixafen plus Prothioconazole

1_Trade_NameManufacturerForm
AVIATOR XPRO FOLIAR FUNGICIDEBAYER CROPSCIENCE PTY LTDEMULSIFIABLE CONCENTRATE

4. ACTIVE INGREDIENTS: Bixafen75g/L+Prothioconazole 150g/L

5. COST: $60.00 per L or kg.

6. CHEMICAL GROUP: 7,3.

7. RELATED PESTICIDES:

Bixafen75g/L+Prothioconazole 150g/L

8. GENERAL DESCRIPTION:

An agricultural fungicide for the control of blackleg in canola. The prothioconazole portion will control cercospora leaf spots and puccinia rusts.

9. APPLICATION METHODS AND TIPS:

Best results in fine weather.
Don't use adjuvants. Avoid multi way mixes.
Do not apply to waterlogged soils or if heavy rain or irrigation will occur within 48 hours.

10. ADJUVANTS, WETTERS, OILS:

Don't use adjuvants as crop dmage may occur.

11. EQUIPMENT:

Use nozzles producing a medium droplet size.

12. SPRAYER WASH OUT AND DECONTAMINATION:

13. WATER OR CARRIER DATA:

60-100 L/ha.

14. WEATHER:

Do not apply during inversions

15. RAINFASTNESS:

2-4 hours

16. SOIL:

17. PLANT HEALTH and OTHER EFFECTS:

18. WITHHOLDING PERIODS:

Harvest: not required
Grazing: 4 weeks
Do not graze milking cows on treated areas.
Export Slaughter interval: 7 days.
Harvest: not required
Grazing: 4 weeks
Do not graze milking cows on treated areas.
Export Slaughter interval: 7 days.

19. PLANT BACK PERIODS or RECROPPING INTERVALS:

20. MODE OF ACTION:

21. PESTICIDE RESISTANCE:

Some species may be resistant or develop resistance with continued application. Rotate with products from alternative groups.

22. TOXICITY:

Poison schedule - S5
Summary: Low toxicity. May cause birth defects. May cause eye damage
Details:
Poison schedule - S5
Mammalian toxicity - Low
Acute oral LD50 - >2000 mg/kg (rats), [For comparison table salt is 3000 mg/kg]
Acute dermal LD50 - >2000 mg/kg (rabbit).
Skin - Slight irritant. Non sensitising
Eye - Severe irritant.
Vapour inhalation - ATE (Mix) > 5 mg/L
Irritating to respiratory system.
Chronic oral toxicity NOEL - ppm for two years.
Not mutagenic or teratogenic (i.e. Does not cause cancer problems).
Assessment toxicity to reproduction
Prothioconazole caused reproduction toxicity in a two-generation study in rats only at dose levels also toxic to the parent animals. The reproduction toxicity seen is related to parental toxicity.
Bixafen did not cause reproductive toxicity in a two-generation study in rats.
Assessment developmental toxicity
Prothioconazole caused developmental toxicity only at dose levels toxic to the dams. The developmental effects seen with Prothioconazole are related to maternal toxicity.
Bixafen did not cause developmental toxicity in rats and rabbits.
Acceptable Daily Intake (ADI) -
Exposure Control:
Components CAS-No. Control parameters
Prothioconazole 178928-70-6 1.4 mg/m3 (SK-ABS)
Bixafen 581809-46-3 0.6 mg/m3 (TWA)

23. TOXICITY SYMPTOMS:

24. FIRST AID:

If SWALLOWED - Do NOT induce vomiting. Rinse mouth with water. Call a physician or poison control center immediately.
If in EYES - Irrigate for 15 minutes with plenty of water. Call a doctor as serious eye damage may occur.
If on SKIN - Rinse with plenty of water, remove contaminated clothing, wash with soap and water.
If INHALED - Remove patient to fresh air.
If patient has symptoms or is concerned contact a doctor immediately.
Advice to doctor - Treat symptomatically.
Gastric lavage is not normally required. However, if a significant amount (more than a mouthful) has been ingested, administer activated charcoal and sodium sulphate.
Call Poisons Information Centre on 13 11 26

25. PROTECTIVE CLOTHING:

Safety goggles and face shield.
Elbow length nitrile rubber gl;oves class 6.
Cotton overalls and washable hat.
Boots.
Wear a respirator with an organic vapours and gas filter mask (protection factor 10)

26 RE ENTRY PERIODS and OTHER SAFETY ISSUES:

After spray has dried or after 1 day for high exposure activities

27. PROPERTIES:

Product appearance - Clear to sightly turbid brown liquid with a weak characteristic odour
Shelf Life -
Product Flammability - Flash point >100C. Ignition temp 375C. Not explosive.
Half life in water - days at pH5 and 35 C.
Water solubility at 25 C. - miscible
Oil solubility -
Octanol:Water ratio at 25 C. -
Prothioconazole: Koc: 1765
Bixafen: Koc: 3869
Prothioconazole: log Pow: 3.82 at 20 °C at pH 7
Bixafen: log Pow: 3.3 at 40 °C
Vapour Pressure at 25 C. -
Dissociation constant - pKa.
Melting point - C.
Boiling point -
Molecular weight -
Density - 1.01 g/cm3
pH: 4-6 at 1%
Viscosity, dynamic -
Viscosity, kinematic: 33.7 mm²/s at 40 °C Shear rate of 20/sec
Surface tension: 32 mN/m at 25 °C in the undiluted form.
Velocity gradient

28. ENVIRONMENTAL FATE:

Summary - Very toxic to aquatic oraganisms.
Birds - Low toxicity.
LD50 (Colinus virginianus (Bobwhite quail)) >2,000 mg/kg for bixafen.
LD50 (Colinus virginianus (Bobwhite quail)) >2,000 mg/kg for prothioconazole.
Fish - High toxicity LC50 = 1.15 mg/L. (Oncorhynchus mykiss (rainbow trout)) 96 h
Invertebrates - Moderate toxicity. EC50 = 3 mg/L (Daphnia magna (Water flea)) 48 h
Algae - Moderate toxicity. EC50 = 2.16 mg/L
Aquatic plants:
EC50 (Skeletonema costatum) 0.046 mg/L. Growth rate; Exposure time: 72 h for prothioconazole.
EC50 (Raphidocelis subcapitata (freshwater green alga)) 1.52 mg/L
Growth rate; Exposure time: 72 h
NOEC (Skeletonema costatum) 0.0073 mg/L Growth rate; Exposure time: 72 h for prothioconazole.
Bees - toxicity.
It has a half life in soil of .
Bixafen and prothioconazole are not rapidly biodegradable
It has an EPA classification for soil mobility that ranges from
Bixafen andprothioconazole are slightly mobile in soils.
Ground water contamination
Accumulation in milk and tissues.
Bioaccumulation
Prothioconazole: Bioconcentration factor (BCF) 19.
Does not bioaccumulate.
Bixafen: Bioconcentration factor (BCF) 695
Does not bioaccumulate.

29. COMPATIBILITY:

See HerbiGuide for compatibility with other herbicides, insecticides and fungicides.
See HerbiGuide for a full list of pesticide compatibilities.
Avoid multi way mixes to reduce the risk of crop damage.
Don't mix with liquid ferilizers prior to flowering.

30. REGISTERED CROPS, INSECTS and DISEASES.

See HerbiGuide Species Solutions Tab for registered uses.

31. GOVERNMENT AND REGULATORY INFORMATION:

Dangerous Goods Class - Dangerous
Hazchem Code - 3Z
Initial Emergency Response Guide IERG -
UN Number - 3082
CAS Numbers: Prothioconazole 178928-70-6
B ixafen 581809-46-3

GHS Classification:
Eye Damage/Irritation: Category 2A
H319 Causes serious eye irritation.
Reproductive toxicity: Category 2
H361 Suspected of damaging fertility or the unborn child.
Specific target organ toxicity - repeated exposure: Category 2
H373 May cause damage to organs through prolonged or repeated exposure.
Acute aquatic toxicity: Category 1
H400 Very toxic to aquatic life.
Chronic aquatic toxicity: Category 1
H410 Very toxic to aquatic life with long lasting effects.

SWA Classification and phrases - Hazardous
R-phrase(s) R48/22 - Harmful: danger of serious damage to health by prolonged exposure or if swallowed.
R63 - Possible risk of harm to the unborn child.
Spray records must be made within 24 hours and kept for 2 years.
5 m downwind buffer zone for wetlands and sensitive areas.

ADG
UN number 3082
Class 9
Subsidiary Risk None
Packaging group III
Description of the goods ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (BIXAFEN SOLUTION)
Hazchem Code 3Z
According to AU01, Environmentally Hazardous Substances in packagings, IBC or any other receptacle not exceeding 500 kg or 500 L are not subject to the ADG Code.
IMDG
UN number 3082
Class 9
Subsidiary Risk None
Packaging group III
EmS F-A , S-F
Marine pollutant YES
Description of the goods ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (BIXAFEN SOLUTION)
IATA
UN number 3082
Class 9
Subsidiary Risk None
Packaging group III
Environm. Hazardous Mark YES
Description of the goods ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S. (BIXAFEN SOLUTION )

32. References:

PROT480_68332-58132.pdf 2014, BIXAPROT_69361-60590.pdf 2017

Acknowledgments:

Collated by HerbiGuide. Phone 08 98444064 or www.HerbiGuide.com.au for more information.