Difenoconazole plus Metalaxyl

1_Trade_NameManufacturerForm
DIVIDEND FORMULA M FUNGICIDE SEED TREATMENTSYNGENTA AUSTRALIA PTY LTDSUSPENSION CONCENTRATE

4. ACTIVE INGREDIENTS: Difenoconazole 92g/L + metalaxyl-m 23 g/L

5. COST: $59.20 per L or kg.

6. CHEMICAL GROUP: 3,4.

7. RELATED PESTICIDES:

Difenoconazole 92g/L + metalaxyl-m 23 g/L
Ipconazole 25g/L + Metalaxyl 20g/L

8. GENERAL DESCRIPTION:

A systemic seed dressing containing 2 active ingredients for the control of many seed and soil borne diseases of cereal seedlings.

9. APPLICATION METHODS AND TIPS:

Seed dressing.
May not provide adequate control of smuts if more than 5% of heads were infected.
Mix wit water before application to seed to make total application volume 400-600 mL/100kg seed.
Ensure thorough coverage of all seeds.

10. ADJUVANTS, WETTERS, OILS:

None recommended.

11. EQUIPMENT:

12. SPRAYER WASH OUT AND DECONTAMINATION:

13. WATER OR CARRIER DATA:

400-600 mL total volume per 100 kg seed for seed treatments.
100 L/ha for ground sprayers.

14. WEATHER:

15. RAINFASTNESS:

16. SOIL:

17. PLANT HEALTH and OTHER EFFECTS:

Does not reduce crop coleoptile length and therefore has less negative interactions with herbicides such as trifluralin, pendimethalin, metolachlor or sulfonyl ureas when used as a seed treatment.

18. WITHHOLDING PERIODS:

19. PLANT BACK PERIODS or RECROPPING INTERVALS:

20. MODE OF ACTION:

Systemic, contact and penetrant activity. Absorbed by the seed and translocated within the seedling.
Difenoconazole is a DMI fungicide and inhibits demethylation during ergostol synthesis. It inhibits the subcuticular growth of mycelium preventing development of symptoms and reduces sporulation.
Metalaxyl-M inhibits RNA synthesis by binding to fungal DNA or or inhibiting RNA polymerase. This inhibits mycelial grwth and prevents spore production.

21. PESTICIDE RESISTANCE:

Some species may be resistant or develop resistance with continued application. Rotate with products from alternative groups.

22. TOXICITY:

Poison schedule - S5
Summary: Low toxicity.
Details:
Poison schedule - S
Mammalian toxicity -
Acute oral LD50 - Low >5050 mg/kg (rats), [For comparison table salt is 3000 mg/kg]
Acute dermal LD50 - Low >5050 mg/kg (rabbit).
Skin - Non irritant. Non sensitizing.
Eye - Slight irritant. High doses of difenoconazole have been associated with cataracts in dogs and hens. Subsequent studies in dogs failed to confirm this.
Vapour inhalation - Low LC50 - >2.73 mg/L air (rat).
Chronic oral toxicity NOEL - ppm for two years.
Not mutagenic or teratogenic (i.e. does not cause cancer or reproductive problems).
High doses of difenoconazole over 2 years have been associated with increased liver tumours in mice but not in rats. It is unlikely to be associated with increased tumours in humans.
High doses of difenoconazole have been associated with liver toxicity and adverse effects on blood cells and platelets.
Acceptable Daily Intake (ADI) -

23. TOXICITY SYMPTOMS:

No records of human poisoning. Symptoms in animals are non specific.

24. FIRST AID:

If SWALLOWED - Do NOT induce vomiting. Give a glass of water and contact Poisons Information Centre on 131 126.
If in EYES - Irrigate for 15 minutes with plenty of water.
If on SKIN - Rinse with plenty of water, remove contaminated clothing, wash with soap and water.
If INHALED - Remove patient to fresh air and keep at rest until recovered.
If patient has symptoms or is concerned contact a doctor immediately.
Advice to doctor - Treat symptomatically. No specific antidote.
Call Poisons Information Centre on 13 11 26

25. PROTECTIVE CLOTHING:

Safety goggles or face shield.
Elbow length PVC gloves.
Cotton overalls and washable hat.
Boots.

26 RE ENTRY PERIODS and OTHER SAFETY ISSUES:

27. PROPERTIES:

Product appearance - Red liquid. Sweet chalky odour.
Shelf Life -
Product Flammability - Non flammable. Non explosive. Not combustible. Flash point > 104C. Auto ignition 435C. May release smoke and hazardous decomposition products when burnt.
Half life in water - days at pH5 and 35 C.
Water solubility at 25 C. - ppm at pH. Disperses in water.
Oil solubility -
Octanol:Water ratio at 25 C. - at pH 5.
Vapour Pressure at 25 C. -
Dissociation constant - pKa.
Melting point - C.
Boiling point - >90C
Molecular weight -
Density - SG 1.19 g/mL
pH 6.5-8.5 (1% in water at 25C)
Not an oxidiser. Non corrosive. Non explosive.

28. ENVIRONMENTAL FATE:

Summary -
Birds - Low toxicity. Metalaxyl-M and difenoconazole are practically non toxic to birds.
Fish - high toxicity LC50 = 0.81 mg/L for difenoconazole on Rainbow Trout. Metalaxyl-M is practically non toxic but difenoconazole is highly toxic to fish
Invertebrates - toxicity.
Bees - Low toxicity. Metalaxyl-M and difenoconazole are practically non toxic to bees.
Algae - Difenoconazole is highly toxic to algae.
It has a half life in soil of .
It has an EPA classification for soil mobility that ranges from
Ground water contamination
Accumulation in milk and tissues.

29. COMPATIBILITY:

See HerbiGuide for compatibility with other herbicides, insecticides and fungicides.
See HerbiGuide for a full list of pesticide compatibilities
Compatible with Actellic, Diacon S and K-Obiol.

30. REGISTERED CROPS, INSECTS and DISEASES.

See HerbiGuide Species Solutions Tab for registered uses.

31. GOVERNMENT AND REGULATORY INFORMATION:

Dangerous Goods Class - Not classed as a dangerous good.
Hazchem Code -
Packaging Group -
EPG -
UN Number -
Worksafe Classification -

32. References:

56880/10/0204 label

Acknowledgments:

Collated by HerbiGuide. Phone 08 98444064 or www.HerbiGuide.com.au for more information.