Difenoconazole plus Metalaxyl-M plus Sedaxane

1_Trade_NameManufacturerForm
VIBRANCE FUNGICIDE SEED TREATMENTSYNGENTA AUSTRALIA PTY LTDFLOWABLE CONCENTRATE FOR SEED TREATMENT

4. ACTIVE INGREDIENTS: Difenoconazole66.2+Metalaxyl-M16.5+Sedaxane13.8g/L

5. COST: $40.04 per L or kg.

6. CHEMICAL GROUP: 3,4,7.

7. RELATED PESTICIDES:

Difenoconazole66.2+Metalaxyl-M16.5+Sedaxane13.8g/L

8. GENERAL DESCRIPTION:

A mixture of three agricultural fungicides used as a seed treatment for the control or suppression of seedling diseases in cereals.

9. APPLICATION METHODS AND TIPS:

Ensure thorough coverage of seed.

10. ADJUVANTS, WETTERS, OILS:

None recommended

11. EQUIPMENT:

12. SPRAYER WASH OUT AND DECONTAMINATION:

13. WATER OR CARRIER DATA:

14. WEATHER:

15. RAINFASTNESS:

16. SOIL:

17. PLANT HEALTH and OTHER EFFECTS:

18. WITHHOLDING PERIODS:

Barley, oats, triticale, wheat:
Harvest: Not required when used as directed
Grazing: Do not graze or cut for stock food for 6 weeks after sowing
Barley, oats, triticale, wheat:
Harvest: Not required when used as directed
Grazing: Do not graze or cut for stock food for 6 weeks after sowing

19. PLANT BACK PERIODS or RECROPPING INTERVALS:

20. MODE OF ACTION:

Systemic.
It is a combination of a DMI, a phenylamide and carboxamide fungicide from fungicide group 3, 4 and 7.

21. PESTICIDE RESISTANCE:

Some species may be resistant or develop resistance with continued application. Rotate with products from alternative groups.

22. TOXICITY:

Poison schedule - S5
Summary: Low toxicity. May irritate eyes.
Details:
Poison schedule - S5
Mammalian toxicity - Low toxicity
Acute oral LD50 - >5000 mg/kg (rats), [For comparison table salt is 3000 mg/kg] Low toxicity
Acute dermal LD50 - >5050 mg/kg (rabbit). Low toxicity
Skin - Non irritant. Not a sensitiser.
Eye - Slight irritant.
Vapour inhalation - LC50 - >2.63 mg/L air (rat). Low toxicity
Chronic oral toxicity NOEL - ppm for two years.
Not mutagenic or teratogenic (i.e. Does not cause cancer or reproductive problems).
Acceptable Daily Intake (ADI) -

Difenoconazole technical has been extensively tested on mammals and in test tube systems. No evidence of mutagenic, teratogenic or reproductive effects was obtained. Chronic 2 year feeding studies revealed no compound related tumourigenic effects in rats, whereas in mice high doses were associated with an increased incidence of liver tumours.
The absence of mutagenic effects and the pronounced restriction of tumour appearance to one organ and one species suggests an underlying promotion process which is frequently seen in mice and which is considered to have no bearing in humans. Repeated high doses of difenoconazole technical were associated with cataracts in dogs and hens. Studies on other species and a subsequent dog study did not confirm this effect. Other effects at high doses included liver toxicity and adverse effects on blood cells and platelets.

Metalaxyl-M, either as technical grade Metalaxyl-M or as a 50% component of technical grade metalaxyl, has been extensively tested on laboratory mammals and in test tube systems. No evidence of mutagenic, teratogenic or reproductive effects was obtained.

Sedaxane technical has been extensively tested on mammals and in test tube systems. No evidence of mutagenic, teratogenic or reproductive effects was obtained. In chronic feeding studies at extremely high doses, numerically higher incidences of uterine, thyroid and liver tumours (male and/or female rats) and liver tumours (male mice) were within the range of normal background variation and are thus considered unrelated to treatment. Some overseas Regulatory Authorities have taken a more conservative position that these high-dose findings are treatment-related in rats and mice. The dose levels where these findings occur are not relevant to human exposure levels.

23. TOXICITY SYMPTOMS:

No specific symtoms.

24. FIRST AID:

If SWALLOWED - seek medical advice immediately and show this container or label. DO NOT induce vomiting.
If in EYES - Irrigate for 15 minutes with plenty of water. Remove contact lenses. Immediate medical attention is required.
If on SKIN - Rinse with plenty of water, remove contaminated clothing, wash with soap and water. If skin irritation persists, see a doctor.
If INHALED - Remove patient to fresh air.If breathing is irregular or stopped, administer artificial respiration. Keep patient warm and at rest. Call a doctor or Poisons Information Centre immediately.
If patient has symptoms or is concerned contact a doctor immediately.
Advice to doctor - Treat symptomatically. There is no specific antidote available
Call Poisons Information Centre on 13 11 26

25. PROTECTIVE CLOTHING:

Safety goggles and face shield.
Elbow length PVC gl;oves.
Cotton overalls and washable hat.
Boots.

26 RE ENTRY PERIODS and OTHER SAFETY ISSUES:

27. PROPERTIES:

Product appearance - Light red to dark red liquid with a slightly aromatic odour.
Shelf Life -
Product Flammability - Flashpoint >100 C. Autoignition temperature 425 C
Half life in water - days at pH5 and 35 C.
Water solubility at 25 C. - Forms a suspensio in water.
Oil solubility -
Octanol:Water ratio at 25 C. - at pH 5.
Vapour Pressure at 25 C. -
Dissociation constant - pKa.
Melting point - C.
Boiling point - ~100 C
Molecular weight -
Density - 1.12 g/cm3
pH - 4-8 at 1% w/v.
Not explosive
Not oxidising
Not combustible
Not corrosive to HDPE

28. ENVIRONMENTAL FATE:

Summary - Toxic to aquatic life.
Birds - toxicity.
Fish - Slight toxicity LC50 >18.7 mg/L, 96 hours, Oncorhynchus mykiss (Rainbow Trout)
Invertebrates - Slight toxicity. EC50 = 13 mg/L, 48 hours, Daphnia magna (Water Flea).
Algae - High toxicity. EbC50 = 0.54 mg/L, 72 hours, Selenastrum Capricornutum (Green algae)
Bees - toxicity.
Persistence -
Difenoconazole
Water Degradation half life = 1 day
Difenoconazole is not persistent in water
Soil Degradation half life = 149-187 days
Difenoconazole is not persistent in soil

Metalaxyl-M
Water Degradation half life = 22.4-47.5 days
Metalaxyl is not persistent in water
Soil Degradation half life = <50 days
Metalaxyl is not persistent in soil

Sedaxane
Not readily biodegradable
Water Degradation half life = >1 year
Sedaxane is persistent in water
Soil Degradation half life = 83 days
Sedaxane is not persistent in soil

It has an EPA classification for soil mobility that ranges from
Difenoconazole - Low mobility in soil
Metalaxyl-M - Low to very high mobility in soil, depending on soil type
Sedaxane - Low to medium mobility in soil
Ground water contamination
Accumulation in milk and tissues.
Bioaccumulative Potential:
Difenoconazole -High potential to bioaccumulate
Metalaxyl-M - Low potential for bioaccumulation
Sedaxane - Does not bioaccumulate

29. COMPATIBILITY:

See HerbiGuide for compatibility with other herbicides, insecticides and fungicides.
See HerbiGuide for a full list of pesticide compatibilities.

30. REGISTERED CROPS, INSECTS and DISEASES.

See HerbiGuide Species Solutions Tab for registered uses.

31. GOVERNMENT AND REGULATORY INFORMATION:

APVMA Numbers: 64098
UN number: 3082
CAS numbers: Difenoconazole 119446-68-3
Metalaxyl-M 70630-17-0 = Mefenoxam
Sedaxane 874967-67-6
OPP Chemical Code:
Hazchem code:
NOHSC classification: Not classified as hazardous under GHS criteria.
Land transport: ADG
Dangerous goods class (ADG): Not a dangerous good in Australia
Sea transport: IMDG
International Maritime Dangerous Goods Code (IMDG):
Proper shipping name: Environmentally Hazardous Substance, Liquid, N.O.S. (difenconazole)
Technical Name:
Hazard Class: 9
ID Number: Product code: A16874F
Packaging group: III
EMS Number:
EPG:
Marine Pollutant:
Air transport: IATA/ICAO
Proper Shipping Name: Environmentally Hazardous Substance, Liquid, N.O.S. (difenconazole)
Technical Name:
ID Number:
Packaging group: III
Cargo Packing Instructions:
Passenger Packing Instructions:
Environmental Hazard:
No Spray Zones:
Records:

32. References:

Acknowledgments:

Collated by HerbiGuide. Phone 08 98444064 or www.HerbiGuide.com.au for more information.